Process for preparing n-alkyl-substituted aminophenols

Details Process for preparing n-alkyl-substituted aminophenols Process for preparing n-alkyl-substituted aminophenols

C - Chemistry, Metallurgy

07

C

260/601.4

C07C 213/08 (2006.01) C07C 213/02 (2006.01) C07C 215/76 (2006.01)

Patent

CA 2022381

A process for preparing an N-alkyl-substituted aminophenol is disclosed, comprising continuously feeding an aldehyde or a ketone to a reaction system containing an organic solvent, a catalyst for reduction, hydrogen, and an aminophenol to conduct a reductive alkylation reaction, wherein said reductive alkylation reaction is carried out while continuously adding an organic carboxylic acid into the reaction system. The process attains a high yield even when the catalyst is repeatedly used and does not cause corrosion of equipment.

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