Process for preparing n-aryl-piperazine derivatives

Details Process for preparing n-aryl-piperazine derivatives Process for preparing n-aryl-piperazine derivatives

C - Chemistry, Metallurgy

07

D

C07D 405/12 (2006.01)

Patent

CA 2560485

Processes for preparing N-aryl-piperazine derivatives of formula I particularly (R)-4-cyano-N-[2-[4-(2,3-dihydro-1,4-benzodioxan-5-yl)-1- piperazinyi~propyl]-N-(2-pyridinyl)-benzamide, are disclosed. Compositions comprising N-aryl~piperazine derivatives and low levels of common impurities are also disclosed. In addition, products produced by the process are disclosed.

L'invention concerne des procédés de préparation de dérivés de N-aryl-pipérazine représentés par la formule (I), et plus particulièrement (R)-4-cyano-N-[2-[4-(2,3-dihydro-1,4-benzodioxan-5-yl)-1-pipérazinyl-propyl]-N-(2-pyridinyl)-benzamide. L'invention concerne également des compositions comprenant des dérivés de N-aryl-pipérazine et de faibles niveaux d'impuretés communes. En outre, l'invention concerne des produits obtenus au moyen des procédés susmentionnés.

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