C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
530/5.02, 530/5.
C07K 5/08 (2006.01) C07K 5/097 (2006.01)
Patent
CA 1247085
PROCESS FOR PREPARING N-CARBOXYALKYLPROLINE- CONTAINING TRIPEPTIDES ABSTRACT OF THE DISCLOSURE Certain N-carboxyalkyl prolyl-containing tripeptides have been prepared which improve kidney function. A species of the group of new compounds is N-(2- carboxyethyl)-L-prolyl-L-alanyl-L-proline which has diuretic activity and increases renal blood flow. The compounds are prepared by chemical reactions which couple an amino acid with a dipeptide.
414962
Gowling Lafleur Henderson Llp
Ltd. Smith Kline & French Canada
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