Process for preparing n-hydroxylamine compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 401/12 (2006.01) C07C 59/01 (2006.01) C07C 211/63 (2006.01) C07C 259/06 (2006.01) C07C 303/28 (2006.01) C07C 309/65 (2006.01) C07D 205/08 (2006.01)

Patent

CA 2499426

The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors. The process makes use .alpha. .beta.-lactam intermediate. Certain optically pure intermediates are also claimed.

L'invention concerne un procédé de préparation d'intermédiaires destinés à préparer certains composés antibactériens à base de <i>N</i>-formyl hydroxylamine qui sont des inhibiteurs de peptide déformylase. Ce procédé utilise comme intermédiaire un .alpha..beta.-lactame. L'invention concerne aussi certains intermédiaires optiquement purs.

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