C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/12 (2006.01) C07C 59/01 (2006.01) C07C 211/63 (2006.01) C07C 259/06 (2006.01) C07C 303/28 (2006.01) C07C 309/65 (2006.01) C07D 205/08 (2006.01)
Patent
CA 2499426
The present invention is directed to a process for preparing intermediates that are useful to prepare certain antibacterial N-formyl hydroxylamine compounds which are peptide deformylase inhibitors. The process makes use .alpha. .beta.-lactam intermediate. Certain optically pure intermediates are also claimed.
L'invention concerne un procédé de préparation d'intermédiaires destinés à préparer certains composés antibactériens à base de <i>N</i>-formyl hydroxylamine qui sont des inhibiteurs de peptide déformylase. Ce procédé utilise comme intermédiaire un .alpha..beta.-lactame. L'invention concerne aussi certains intermédiaires optiquement purs.
Jiang Xinglong
Kapa Prasad Koteswara
Lee George Tien-San
Loeser Eric M.
Prashad Mahavir
Fetherstonhaugh & Co.
Novartis Ag
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