Process for preparing n-protected 4-ketoproline derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 207/24 (2006.01)

Patent

CA 2557017

The present invention is concerned with a process for preparing compounds of the general formula (I). These compounds can preferably be used to prepare bioactive agents. The reaction of the invention starts from the corresponding hydroxy compounds which are oxidized, with Ru catalysis, in a one-phase aqueous system.

Cette invention a pour objet un procédé permettant de préparer des composés représentés par la formule générale (I). Ces composés sont utilisés de préférence pour la préparation d'agents bioactifs. La réaction décrite est effectuée à partir des composés hydroxy correspondants, qui sont oxydés, à l'aide d'une catalyse Ru, dans un système aqueux à une seule phase.

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