Process for preparing new 1,3-dihydro 4-(1-hydroxy...

Details Process for preparing new 1,3-dihydro 4-(1-hydroxy... Process for preparing new 1,3-dihydro 4-(1-hydroxy...

C - Chemistry, Metallurgy

07

D

260/320

C07D 209/34 (2006.01) C07D 209/08 (2006.01) C07D 209/30 (2006.01)

Patent

CA 1204445

PRECIS DE LA DIVULGATION: L'invention concerne la préparation de nouveaux dérivés de la 1,3-dihydro 4-[1-hydroxy 2-amino éthyl] 2H- indol-2-one et de leurs sels d'addition avec les acides minéraux ou organiques, de formule (I): Image dans laquelle: R = H, alc, C1-C8; ou phénylalcoyle C7-C10, R1, R2 = H, Alc linéaire ou ramifié C1-C3 (substitué ou non par Hal, OH, Aryle, Aryloxy); cycloalc C3-C7; cycloalcoylalc C4-C7, alcényle C3-C6; ou alcynyle C3-C6. Les nouveaux dérivés de formule I sont utiles comme médicaments en raison de leurs propriétés antihypertensives et hypotensives et pour certains de leurs propriétés anti-inflammatoires.

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