C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/291.3, 260/3
C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 207/20 (2006.01) C07D 207/263 (2006.01) C07D 207/27 (2006.01) C07D 211/26 (2006.01) C07D 211/34 (2006.01) C07D 211/70 (2006.01) C07D 211/76 (2006.01)
Patent
CA 1039731
A B S T R A C T The invention provides novel 2-methoxy-benzamide derivatives of the formula: Image (I) in which n is 1 or 2; R1 represents a cycloalkyl-alkyl radical of formula: Image , a phenylalkyl radical of formula Image (in which m is an integer from 2 to 5, A is a linear or branched alkylene chain of 1 to 4 carbon atoms, and R4 is hydrogen, halogen, especially fluorine or chlorine, trifluoromethyl, or alkyl or alkoxy of 1 to 3 carbon atoms), CNCH2-CH2-, CH?C-CH2-, Image , or Image ; R2 is either chlorine, SO2R5 (in which R5 is alkyl or 1 to 4 carbon atoms), or SO2NR6R7 (in which, R6 and R7, which are identical or different, represent, independently of one another, hydrogen or alkyl of 1 to 4 carbon atoms); and R3 is hydrogen or alkyl of 1 to 4 carbon atoms; in the form of racemates or optical isomers, and their pharmaceutically acceptable acid addition salts, which are useful in the treatment of psychosomatic and psychotic disturbances.
241723
Giudicelli Don P.r.l.
Jalfre Maurice
Kaplan Jean-Pierre
Manoury Philippe M.j.
Najer Henry
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