Process for preparing new 2-methoxy-benzamide derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 207/08 (2006.01) C07D 207/09 (2006.01) C07D 207/20 (2006.01) C07D 207/263 (2006.01) C07D 207/27 (2006.01) C07D 211/26 (2006.01) C07D 211/34 (2006.01) C07D 211/70 (2006.01) C07D 211/76 (2006.01)

Patent

CA 1039731

A B S T R A C T The invention provides novel 2-methoxy-benzamide derivatives of the formula: Image (I) in which n is 1 or 2; R1 represents a cycloalkyl-alkyl radical of formula: Image , a phenylalkyl radical of formula Image (in which m is an integer from 2 to 5, A is a linear or branched alkylene chain of 1 to 4 carbon atoms, and R4 is hydrogen, halogen, especially fluorine or chlorine, trifluoromethyl, or alkyl or alkoxy of 1 to 3 carbon atoms), CNCH2-CH2-, CH?C-CH2-, Image , or Image ; R2 is either chlorine, SO2R5 (in which R5 is alkyl or 1 to 4 carbon atoms), or SO2NR6R7 (in which, R6 and R7, which are identical or different, represent, independently of one another, hydrogen or alkyl of 1 to 4 carbon atoms); and R3 is hydrogen or alkyl of 1 to 4 carbon atoms; in the form of racemates or optical isomers, and their pharmaceutically acceptable acid addition salts, which are useful in the treatment of psychosomatic and psychotic disturbances.

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