Process for preparing new aminated 4-phenyl 4-oxo 2-butenoic...

C - Chemistry – Metallurgy – 07 – C

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260/515.1, 260/3

C07C 275/42 (2006.01)

Patent

CA 1189526

PRECIS DE LA DIVULGATION: L'invention concerne un procédé pour la prépa- ration des composés (I): Image (I) où R1 et R2 représentent un hydrogène, un alkyle (1-4c), CONH2, CO2alc1, dans lequel alc1 est un alkyle (2-8c) ou SO2alc2, dans lequel alc2 est un alkyle (1-8c), R est un hydrogène ou un alkyle (1-8c), ainsi que leurs sels alcalins, alcalino-terreux, d'ammonium ou d'amines. Les composés (I) et leurs sels sont utiles notamment comme anti-ulcéreux,anti-sécrétoires gastriques et cytoprotec- teurs.

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