Process for preparing novel derivatives of...

C - Chemistry – Metallurgy – 07 – D

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260/38, 260/581.

C07D 317/72 (2006.01) C07J 1/00 (2006.01)

Patent

CA 1132535

PRECIS DE LA DIVULGATION : L'invention concerne de nouveaux dérivés de la 4,5- séco estrane 3,5,17-trione, de formule I : Image I dans laquelle R1 est un alcoyle de 1 à 3 atomes de carbone, R2 un hydrogène ou un alcoyle de 1 à 5 atomes de carbone et K et X' identiques ou différents représentent une cétone bloquée sous forme de cétal, leur procédé de préparation, les inter- médiaires nouveaux obtenus et leur application à la préparation de composés thérapeutiquement actifs et ayant en particulier une activitéanti-androgène.

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