Process for preparing novel esters from 1-methyl-4-piperidinol

C - Chemistry – Metallurgy – 07 – D

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C07D 211/46 (2006.01) C07D 401/12 (2006.01)

Patent

CA 1123830

P R E C I S Des esters du méthyl-1 pipéridinol-4 de formule Image dans laquelle : R est chloro-7 quinolyle-4, trifluorométhyl-7 quinolyle-4 ou trifluorométhyl-8 quinolyle-4, et leurs sels d'addition avec des acides appropries, ont été préparés par réaction d'un dérivé chloré de formule R - Cl avec l'amino-2 benzoate de méthyl-1 pipéridyle-4. Ces nouveaux composés et leurs sels physiologiquement tolé- rables peuvent être utilisés en thérapeutique notamment dans le traitement des manifestations inflammatoires et douloureuses.

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