C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/488.8, 260/4
C07C 69/30 (2006.01) C07C 69/708 (2006.01)
Patent
CA 1164012
ABSTRACT OF THE DISCLOSURE: A process for preparing a mixture of glyceryl 1,3-bis-(di-n-propylacetate) and 1,2-bis-(di-n-propylacetate) in a ratio of about 1.43 to about 1,54, whereby one equivalent of 1.3-dichloro-2-propanol is esterified at a temperature between 100 and 110°C and for 5 to 10 hours with two equiva- lents of an alkali metal salt of di-n-propylacetic acid in N,N-dimethylformamide as solvent followed by rectification of the mixture of esters so obtained. The esters according to the invention and mixtures thereof are endowed with biochemical and pharmacological properties likeby to render them particularly useful in the treatment of pathological conditions due to disturbances of the central nervous systems and disorders relating to the field neutropsychiatry.
415623
Chignac Michel
Eymard Pierre
Ferrandes Bernard
Grain Claude
Jammot Fernand
Robic Robic & Associes/associates
Sanofi-Synthelabo
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