Process for preparing novel guanidinothiazole compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 277/38 (2006.01) C07D 277/40 (2006.01) C07D 277/48 (2006.01)

Patent

CA 1134836

PROCESS FOR PREPARING NOVEL GUANIDINOTHIAZOLE COMPOUNDS Abstract of the Disclosure Process for preparing novel guanidinothiazole compounds of the general formula: Image wherein R represents a hydrogen atom or a lower alkyl group; R1 represents an amino group, a lower alkyl group, a halogeno lower alkyl group, a substituted- or unsubstituted-aryl group, a mono- or di-lower alkylamino group, an arylamino group or an aralkylamino group; R2 represents a hydrogen atom, a lower alkyl group, a lower alkenyl group or a lower alkynyl group; Y represents a sulfur atom or a methylene group; m and n, each represents an integer of 1 - 3; and the pharmacologically acceptable acid addition salts thereof. The guanidinothiazole compounds having gastric acid secretion inhibitors.

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