Process for preparing novel pyrimidone compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 401/00 (2006.01) C07D 213/55 (2006.01) C07D 215/14 (2006.01) C07D 231/12 (2006.01) C07D 235/16 (2006.01) C07D 239/36 (2006.01) C07D 277/48 (2006.01) C07D 295/096 (2006.01) C07D 295/15 (2006.01) C07D 317/60 (2006.01) C07D 317/62 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1211111

ABSTRACT OF INVENTION A compound of the formula: Image wherein R1 represents a hydrogen atom, an alkyl group, a lower alkenyl group, a lower alkinyl group, a phenyl group, a cycloalkylmethyl group, an unsubstituted or substituted aralkyl group, or the group shown by Image wherein A represents a lower alkylene group, R3 and R4, which may be the same or different, represent an lower alkyl group, and R3 and R4 may combine to form with nitrogen atom of Image a piperiding ring or a pyrrolidine ring; R2 represents a hydrogen atom, a lower alkyl group or a trifluoromethyl group; Y represents a heterocyclic group represented by the formula: Image wherein R represents a hydrogen atom, or a lower alkyl group; B represents an oxygen atom or a sulfur atom; - 2 - m represents an integer of 0 to 3; n represents an integer of 1 to 3; and the pharmacologically acceptable salts thereof. The compounds are useful as gastric acid secretion inhibitors.

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