Process for preparing optically active imidazolylpropanol...

Details Process for preparing optically active imidazolylpropanol... Process for preparing optically active imidazolylpropanol...

C - Chemistry, Metallurgy

07

D

260/315.25

C07D 233/60 (2006.01)

Patent

CA 1191856

-19- ABSTRACT PROCESS FOR PREPARING OPTICALLY ACTIVE IMIDAZOLYLPROPANOL COMPOUNDS, AND INTERMEDIATE THEREIN An optically active imidazolylpropanol compound of the formula: Image (I) wherein n is an integer of 3 or 4, and its acid addition salts, which is useful as an antifungal agent, prepared by reacting an imidazolylthiol of the formula: Image (II) with an alkylating agent of the formula: CH3-(CH2)n-X (III) whrein n is as defined above and X is a halogen atom, an alkylsulfonyloxy group or an arylsulfonyloxy group.

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