Process for preparing organic compounds

Details Process for preparing organic compounds Process for preparing organic compounds

C - Chemistry, Metallurgy

07

C

C07C 29/36 (2006.01) C07C 29/44 (2006.01) C07C 41/18 (2006.01) C07C 41/30 (2006.01) C07C 43/23 (2006.01)

Patent

CA 2644465

Process for preparing a compound of the formula (I) in which R1 and R2 are each independently H, C1-C8-alkyl, halogen, polyhalo-C1-C8-alkoxy, polyhalo-C1-C8-alkyl, C1-C8-alkoxy, C1-C8-alkoxy-C1-C8-alkyl, or C1-C8-alkoxy-C1-C8-alkoxy, where R1 and R2 are not both H, and R3 is C1-C8-alkyl, which is characterized in that a) a compound of the formula (II) in which R1 and R2 are each as defined above and X is Br, I, triflate, toyslate or mesylate is reacted with prop-2-yn-1-ol to give the compound of the formula (III), b) the compound of the formula (III) is reacted with an alkyl-metal compound in which "alkyl" is as defined above for R3 to give a compound of the formula (I).

L'invention concerne un procédé de préparation d'un composé de formule (I) dans laquelle R1 et R2 représentent chacun indépendamment H, C1-C8-alkyle, halogène, polyhalo-C1-C8-alcoxy, polyhalo-C1-C8-alkyle, C1-C8-alcoxy, C1-C8-alcoxy-C1-C8-alkyle, ou C1-C8-alcoxy-C1-C8-alcoxy; R1 et R2 ne représentant pas tous les deux H; et R3 représente C1-C8-alkyle. Ce procédé est caractérisé en ce que : a) un composé de formule (II) dans laquelle R1 et R2 ont la définition indiquée précédemment et X représente Br, I, triflate, toyslate ou mésylate, est amené à réagir avec prop-2-yn-1-ol afin d'obtenir le composé de formule (III); b) le composé de formule (III) est amené à réagir avec un composé alkyle-métal dans lequel "alkyle" a la définition indiquée précédemment pour R3 afin d'obtenir un composé de formule (I).

Affiliated with

Also associated with

Rating

Process for preparing organic compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for preparing organic compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for preparing organic compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1938901