Process for preparing osteogenesis promoting substance

Details Process for preparing osteogenesis promoting substance Process for preparing osteogenesis promoting substance

A - Human Necessities

61

K

A61K 35/32 (2006.01) A61L 27/36 (2006.01) C07K 4/12 (2006.01)

Patent

CA 2050744

ABSTRACT OF THE DISCLOSURE A process for preparing an osteogenesis promoting substance, which comprises extracting a demineralized bone powder with a solution of chaotorpic reagent, subjecting the extracted solution to ultrafiltration to collect a fraction containing substances ranging from 1,000 to 100,000 daltons as molecular weight, dialyzing the collected fraction and collecting the water-insoluble fraction from the dialyzing liquid. The osteogenesis promoting substance prepared by the present invention is useful as a bone repairing agent and a bone grafting agent.

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