Process for preparing oxiranemethanamine derivatives

C - Chemistry – Metallurgy – 07 – D

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C07D 303/46 (2006.01) C07C 215/28 (2006.01) C07D 301/02 (2006.01) C07D 303/36 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2251066

A process for preparing oxiranemethane derivatives which are useful as intermediates for preparing aspartyl protease inhibitors comprising the steps of activating an aminodiol, acylating the aminodiol and reacting the acylated aminodiol with a base to form an epoxy compound.

Dans un procédé de préparation de dérivés d'oxiraneméthane utiles comme intermédiaires dans la préparation d'inhibiteurs de l'aspartyle protéase, on active un aminodiol, on l'acyle et on met à réagir l'aminodiol acylé avec une base de façon à obtenir un composé époxy.

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