Process for preparing oxymorphone, naltrexone, and...

Details Process for preparing oxymorphone, naltrexone, and... Process for preparing oxymorphone, naltrexone, and...

C - Chemistry, Metallurgy

07

D

C07D 489/08 (2006.01) C07D 489/12 (2006.01) A61K 31/485 (2006.01) C07D 489/02 (2006.01)

Patent

CA 2674917

Methods are provided which include converting oripavine to other opiates, including converting oripavine to naltrexone, buprenorphine, 14-hydroxymorphinone and/or converting 14-hydroxymorphinone to oxymorphone. Purification and salt formation are optionally included.

L'invention concerne des procédés qui comprennent la conversion de l'oripavine en d'autres opiacés, comprenant la conversion de l'oripavine en naltrexone, buprénorphine, 14-hydroxymorphinone et/ou la conversion du 14-hydroxymorphinone en oxymorphone. La purification et la formation de sel sont facultativement incluses.

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