Process for preparing pentanoic diacid derivatives

Details Process for preparing pentanoic diacid derivatives Process for preparing pentanoic diacid derivatives

C - Chemistry, Metallurgy

07

C

C07C 235/06 (2006.01) C07C 51/16 (2006.01) C07C 51/367 (2006.01) C07C 59/245 (2006.01) C07C 67/31 (2006.01) C07C 67/313 (2006.01) C07C 69/675 (2006.01) C07C 231/12 (2006.01) C07D 239/42 (2006.01)

Patent

CA 2696381

The present invention relates to a process for preparing pentanoic diacid derivatives useful for preparing pyrimidine derivatives, in particular as intermediates useful for preparing pyrimidine derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, such as HMG-CoA reductase inhibitors, e.g. rosuvastatin.

La présente invention porte sur un procédé pour préparer des dérivés de diacide pentanoïque utiles pour préparer des dérivés de pyrimidine, en particulier en tant qu'intermédiaires utiles pour préparer des dérivés de pyrimidine d'une classe qui est efficace pour inhiber la biosynthèse du cholestérol chez les êtres humains, notamment les inhibiteurs de la HMG-CoA réductase, par exemple, la rosuvastatine.

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