Process for preparing pharmaceutical compounds

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 229/00 (2006.01) C07D 209/02 (2006.01) C07D 233/32 (2006.01) C07D 233/54 (2006.01) C07D 277/30 (2006.01) C07D 291/00 (2006.01) C07D 303/02 (2006.01) C07D 303/08 (2006.01) C07D 303/12 (2006.01) C07D 303/36 (2006.01) C07D 303/38 (2006.01) C07D 303/40 (2006.01) C07D 303/46 (2006.01) C07D 307/34 (2006.01) C07D 317/46 (2006.01) C07D 333/52 (2006.01) C07D 333/72 (2006.01) C07D 405/00 (2006.01) C07D 405/02 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 409/00 (2006.01) C07D 4

Patent

CA 2281108

Cryptophycin compounds may be prepared utilizing an epoxidation step early in the synthetic process under the conditions set forth herein. This invention also relates to novel intermediates generated by this early epoxidation process.

On peut préparer des composés de cryptophycine, en utilisant une étape d'époxydation dans la phase initiale du processus de synthèse, aux conditions établies dans les pièces descriptives. Cette invention se rapporte également à de nouveaux intermédiaires produits par ce processus d'époxidation en phase initiale.

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