Process for preparing phenyl butyronitriles and perfumery...

C - Chemistry – Metallurgy – 07 – C

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C07C 255/33 (2006.01) C07C 253/30 (2006.01) C11B 9/00 (2006.01) C11D 3/395 (2006.01) A61K 7/46 (1995.01)

Patent

CA 2070693

Described is the use in imparting, augmenting or enhancing aromas to or in perfume compositions, colognes and perfumed articles by admixing therewith an aroma imparting, augmenting or enhancing quantity of 2,2-dimethyl-4-phenyl valeronitrile defined according to the structure: Image . Also described herein is a process for preparing phenyl buty- ronitriles by reacting isobutyronitrile having the structure: ?CN with a styrene derivative defined according to the structure: Image according to the reaction: Image + Image Image in the presence of a catalyst selected from the group consisting of sodium hydride and lithium diisopropyl amide having the structure: Image at a temperature in the range of from about 90°C up to about 130°C yielding more than about 65% by weight of product wherein R1 and R2 are the same or different and each represents hydrogen or methyl.

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