C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/78 (2006.01) C07C 221/00 (2006.01) C07C 225/10 (2006.01) C07C 231/02 (2006.01) C07C 235/80 (2006.01) C07D 211/22 (2006.01) C07D 211/90 (2006.01) C07C 225/08 (2006.01)
Patent
CA 2433605
The present invention relates to a process for preparing (.plusmn.)-trans-4-p- fluorophenyl-3-hydroxymethyl-1-methylpiperidine of formula (I). The present invention also relates to novel intermediates of the formula (IX) and (IX') methods for preparing said intermediates and the use of said compounds for preparing Paroxetine and Omiloxetine.
La présente invention concerne un procédé de préparation de (?)-trans-4-p-fluorophényl-3-hydroxyméthyl-1-méthylpipéridine de la formule (1). L'invention se rapporte également à de nouveaux intermédiaires des formules (9) et (9'), à des procédés de préparation de ces intermédiaires et à l'utilisation de ces composés dans la préparation de paroxétine et d'omiloxétine.
Armengol Miguel P.
Camps Francesc X.
Castello Josep M.
Fernandez-Cano Diego
Foguet Rafael
Ferrer Internacional S.a.
Robic
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