Process for preparing preparations for oral administration

Details Process for preparing preparations for oral administration Process for preparing preparations for oral administration

A - Human Necessities

61

K

167/169

A61K 9/16 (2006.01) A61K 31/00 (2006.01)

Patent

CA 1069047

ABSTRACT OF THE DISCLOSURE A process for preparing preparations for oral adminis- tration which do not have a bitter taste which comprises either dissolving a bitter taste-masking substance at a high con- centration in a solvent to be used for dissolving or suspending a bitter active ingredient and adding the active ingredient to the resulting solution followed by kneading, or kneading a solution or suspension in which a bitter active ingredient has been dissolved or suspended with the bitter taste-masking sub- stance,adding silicic acid anhydride to the resulting kneaded substance to form a powder and granulating the powder using a solution of the bitter taste-masking substance in a fluidized bed granulator.

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