Process for preparing primycin-salts

Details Process for preparing primycin-salts Process for preparing primycin-salts

C - Chemistry, Metallurgy

07

H

167/185, 260/228

C07H 17/08 (2006.01) A61K 31/70 (2006.01)

Patent

CA 1257254

Abstract The invention relates to salts of primycin formed with an organic acid - preferably a C1-16 aliphatic carboxylic acid, a halogenated carboxylic acid, an aliphatic dicarboxylic acid, an aromatic carboxylic acid, a substituted aromatic carboxylic acid or an organic sulfonic acid - or an inorganic acid - pre- ferably a hydrohalogenic acid. There is furtheron provided a process for the preparation of new primycin salts which comprises reacting a suspension of primycin sulfate formed with an aliphatic alcohol containing 1-4 carbon atoms with a barium salt. The new primycin salts of the present invention possess excellent antibiotic properties.

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