Process for preparing proteins

C - Chemistry – Metallurgy – 12 – N

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195/122.6, 195/3

C12N 5/02 (2006.01) C12N 1/36 (2006.01) C12N 1/38 (2006.01) C12N 5/00 (2006.01) C12N 9/72 (2006.01) C12P 21/00 (2006.01)

Patent

CA 1341400

A method of increasing the production of a protein by cells in culture, which method includes the step of adding to the culture medium an effective amount of an inducer of protein production selected from thioglycolic acid, thiodiglycolic acid, L- cysteine, glutathione, butyryl choline bromide, butyryl choline chloride, nonactic acid, furan fatty acid, ascorbic acid, aphidicolin, 6-hydroxy- 4,6-dimethyl-3-hepten-2-one, fusaric acid, mevalonic acid, trans-anhydromevalonic acid, anhydromevalonic acid lactone, cis-anhydromevalonic acid lactone, D-.alpha.-hydroxy-substituted (C3 or C4) aliphatic mono- or dicarboxylic acid or salts thereof.

579969

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