Process for preparing purified immune globulin (igg)

Details Process for preparing purified immune globulin (igg) Process for preparing purified immune globulin (igg)

A - Human Necessities

61

K

167/139

A61K 39/395 (2006.01) C07K 16/06 (2006.01)

Patent

CA 1201063

ABSTRACT An improved process for preparing animal plasma frac- tions, particularly human plasma fractions, containing puri- fied immune globulin (IgG) which is suitable for intravenous use comprises the use of a dilute solution containing IgG as starting material. This solution is subjected to a two stage process of separation, firstly on an anion exchange column containing an agarose cross-linked anionic exchange resin and secondly, on an anion exchange column containing a different anionic exchange resin. The eluate thus obtained contains pure IgG an may, if desired, be freeze-dried to provide a solid composition of matter containing IgG.

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