C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/10 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07H 1/08 (2006.01)
Patent
CA 2245576
The invention relates to a nucleic acid preparation with a content of below 1 % protein, preferably below 0.1 % protein, free of ethidium bromide, phenol, caesium chloride and detergents based on octyl phenol poly(ethylene glycol ether)n and with a content of below 1 EU/mg DNA of endotoxins. Said preparation is suitable as a drug particularly in gene therapy.
L'invention concerne une préparation d'acide nucléique contenant moins de 1 % de protéine, de préférence moins de 0,1 % de protéine, dépourvue de bromure d'éthidium, de phénol de chlorure de césium et de détergents à base d'octylphénolpoly(éthylèneglycoléther)n, et présentant une teneur en endotoxines inférieure à 1 EU/mg d'ADN. Cette préparation s'utilise comme médicament, notamment en thérapie génique.
Boehringer Mannheim Gmbh
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Roche Diagnostics Gmbh
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