Process for preparing pyrazolobenzoxazine derivatives and...

C - Chemistry – Metallurgy – 07 – D

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C07D 498/04 (2006.01) A61K 31/535 (2006.01) C07D 265/36 (2006.01)

Patent

CA 1266648

PRECIS DE LA DIVULGATION: L'invention concerne un procédé pour la préparation des nouveaux dérivés de la pyrazolobenzoxazine ainsi que leurs sels avec les acides, de formule: Image où R est hydrogène, Alkyle (C1-C5), cycloalkylalkyle (C4-C7), Aralkyle éventuellement substitué, Alkényle, Alkynyle (C3-C5) et X est hydrogène ou -CH2-S-Alk, Alk représentant un alkyle (C1-C5). Les dérivés obtenus par le procédé objet de l'in- vention sont doués de propriétés agonistes dopaminergiques, hypotensives et antihypertensives ainsi que de propriétés antianoxiques.

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