Process for preparing pyridine derivatives with a fused...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/04 (2006.01) C07D 221/04 (2006.01)

Patent

CA 1055946

PROCESS FOR PREPARING PYRIDINE DERIVATIVES WITH A FUSED CARBOCYCLIC RING ABSTRACT The invention concerns a novel process for preparing 5,6,7,8-tetrahydroquinolines and related compounds substituted by a monosubstituted thioamide group in which a metal derivative of the 5,6,7,8,-tetrahydroquinoline or related compound is re- acted with an alkyl, aryl or aralkyl isothiocyanate and the product is treated with hydrogen ions. The compounds produced by the process of the invention are anti-ulcer agents.

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