Process for preparing pyrimidine derivatives

Details Process for preparing pyrimidine derivatives Process for preparing pyrimidine derivatives

C - Chemistry, Metallurgy

07

D

C07D 239/42 (2006.01)

Patent

CA 2696195

The present invention relates to a process for preparing pyrimidine derivatives, in particular as intermediates useful for preparing pyrimidine derivatives of a class that is effective at inhibiting the biosynthesis of cholesterol in humans, such as HMG-CoA reductase inhibitors, e.g. rosuvastatin.

La présente invention porte sur un procédé de préparation de dérivés de pyrimidine, en particulier en tant qu'intermédiaires utiles pour préparer des dérivés de pyrimidine d'une classe qui est efficace pour inhiber la biosynthèse du cholestérol chez les êtres humains, tels que les inhibiteurs de la HMG-CoA réductase, par exemple la rosuvastatine.

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