Process for preparing quetiapine fumarate

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/04 (2006.01)

Patent

CA 2603795

Provided is a novel synthesis of quetiapine, and pharmaceutically acceptable salts thereof, in which an alkali metal halide or siliyl halide is included in the reaction mixture.

L'invention concerne une nouvelle synthèse de quétiapine et des sels associés acceptables pharmaceutiquement. Au cours de ladite synthèse, un halogénure métallique alcalin ou un halogénure de siliyl est incorporé dans le mélange de réaction.

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