Process for preparing spray-dried powders containing a...

Details Process for preparing spray-dried powders containing a... Process for preparing spray-dried powders containing a...

A - Human Necessities

61

K

167/149

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 31/375 (2006.01)

Patent

CA 1243956

ABSTRACT OF THE DISCLOSURE: A process for preparing a water-soluble, vitamin containing powder directly compressible into a tablet, comprising spray drying (a) an aqueous slurry of a water-soluble vitamin and a binder; (b) preferably an adsorbent and (c) a lubricant. Particularly useful water-soluble vitamins are ascorbic acid, sodium ascorbate, and calcium ascorbate. In the process, the lubricant is spray dried along with the other components. The powders prepared by this process are directly compressible into tablets and will not demix.

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