Process for preparing substituted 1,3-oxathiolanes with...

C - Chemistry – Metallurgy – 07 – D

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C07D 411/04 (2006.01) C07D 327/04 (2006.01) C07D 405/04 (2006.01) C07D 411/14 (2006.01) C07D 471/04 (2006.01) C07D 473/00 (2006.01) C07D 473/40 (2006.01) C07D 487/04 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2152269

Disclosed an processes for preparing compounds of formula (I) and pharmaceutically acceptable salts or esters thereof, wherein R2 is a purine or pyrimidine base or an analogue or derivative thereof; and Z is S, S=O or SO2. The invention also relates to intermediates of use in the preparation of these compounds.

L'invention concerne des procédés qui permettent de préparer des composés de la formule (I), ainsi que leurs sels ou esters pharmaceutiquement acceptables, formule dans laquelle R2 représente une base purine ou pyrimidine ou un de ses analogues ou dérivés; et Z représente S, S = O ou SO2. L'invention concerne aussi des intermédiaires utiles dans la préparation de ces composés.

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