Process for preparing substituted imidazole derivatives and...

C - Chemistry – Metallurgy – 07 – D

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C07D 233/54 (2006.01) C07D 233/84 (2006.01)

Patent

CA 2511969

The invention relates to a process for preparing substituted imidazole derivatives of formula (I) and acid addition salts thereof (I) in which formula Y is -CH2- or -CO-, R1 is H, halo or hydroxy, R2 is H or halo and R3 is H or lower alkyl, starting from a compound of formula (II) wherein Y, R1, R2 and R3 are as defined above. The invention also relates to intermediates and their preparation.

L'invention concerne un procédé de préparation de dérivés d'imidazole substitués, représentés par la formule (I), et de sels d'addition d'acides de ces composés à partir d'un composé de formule (II). Dans lesdites formules, Y représente un groupe -CH¿2?- ou -CO-, R¿1? représente un atome d'hydrogène ou un groupe halo ou hydroxy, R¿2? représente un atome d'hydrogène ou un groupe halo et R¿3? représente un atome d'hydrogène ou un groupe alkyle inférieur. L'invention concerne également des produits intermédiaires et leur préparation.

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