Process for preparing tannate tablet capsule or other solid...

A - Human Necessities – 61 – K

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Details

A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/26 (2006.01) A61K 9/48 (2006.01) A61K 31/7024 (2006.01) A61K 45/06 (2006.01) C07H 5/06 (2006.01)

Patent

CA 2482013

An active pharmaceutical ingredient is combined with tannic acid to form a tannate salt complex of the active ingredient. The active ingredient tannate salt complex without isolation or purification is then blended with pharmaceutically acceptable excipients to form a granulate which is processed into a tablet or capsule to generate a therapeutic dosage form.

L'invention concerne un ingrédient pharmaceutique actif combiné à de l'acide tannique pour former un complexe de sels de tannate de l'ingrédient actif. Le complexe de sels de tannate de l'ingrédient actif, sans être isolé ou purifié, est alors mélangé avec des excipients acceptables d'un point de vue pharmaceutique pour former un granulé, traité de manière à obtenir un comprimé ou une capsule et générer une forme de dosage thérapeutique.

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