Process for preparing telmisartan

Details Process for preparing telmisartan Process for preparing telmisartan

C - Chemistry, Metallurgy

07

D

C07D 235/18 (2006.01) A61K 31/4184 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2581723

Provided are processes for preparing telmisartan alkyl ester and telmisartan using environmentally friendly organic solvents that are easily removed from the reaction mixture, wherein a telmisartan alkyl ester is isolated and hydrolyzed to form telmisartan or the telmisartan is prepared using a synthesis in a single reaction vessel.

L'invention concerne des méthodes de préparation d'un alkyl-ester de telmisartan, et un telmisartan utilisant des solvants organiques écologiques qui s'éliminent facilement du mélange réactionnel. Un alkyl-ester de telmisartan est isolé et hydrolysé pour former le telmisartan, ou le telmisartan est préparé par synthèse dans une cuve de réaction unique.

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