Process for preparing terbinafine by using platinum as catalyst

Details Process for preparing terbinafine by using platinum as catalyst Process for preparing terbinafine by using platinum as catalyst

C - Chemistry, Metallurgy

07

C

C07C 209/68 (2006.01) C07C 211/30 (2006.01)

Patent

CA 2507587

A process for the preparation of terbinafine, comprising the reaction of a compound of formula (II), or a salt thereof, wherein X is a leaving group, with tert-butylacetylene, in the presence of a platinum catalyst.

L'invention concerne un procédé de préparation de terbinafine, consistant à faire réagir un composé représenté par la formule (II), ou un sel de celui-ci, X représentant un groupe partant, avec du tert-butylacétylène, en présence d'un catalyseur platine.

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