Process for producing 1,4-dihydroxy-2-naphthoic acid

C - Chemistry – Metallurgy – 12 – P

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C12P 7/42 (2006.01) A23L 1/30 (2006.01) A61K 31/192 (2006.01) A61P 1/04 (2006.01) A61P 1/12 (2006.01) A61P 1/14 (2006.01) A61P 19/08 (2006.01)

Patent

CA 2457055

A composition containing 1,4-dihydroxy-2-naphthoic acid at a high concentration is obtained by intracellularly and extracellularly producing 1,4- dihydroxy-2-naphthoic acid using a bacterium belonging to the genus Propionibacterium and collecting it. This composition is efficacious in improving enteric flora, relieving abdominal unpleasantness in association with the intake of milk and preventing metabolic bone diseases.

L'invention concerne l'élaboration d'une composition renfermant de l'acide 1,4-dihydroxy-2-naphtoïque à concentration élevée. A cet effet, on procède à l'élaboration intracellulaire et extracellulaire d'acide1,4-dihydroxy-2-naphtoïque au moyen d'une bactérie du genre Proponiobacterium afin de recueillir ensuite ledit acide. La composition considérée est efficace pour améliorer la flore intestinale, soulager l'inconfort abdominal lié à l'absorption de lait, et prévenir les maladies métaboliques osseuses.

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