Process for producing 1-acyl-2-pyrazoline derivative

C - Chemistry – Metallurgy – 07 – D

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C07D 231/06 (2006.01) C07D 401/06 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01)

Patent

CA 1319366

ABSTRACT OF THE DISCLOSURE 1-Acyl-2-pyrazoline derivatives represented by the formula Image where R1 denotes a hydrogen atom, pyridyl group, pyrazinyl group, alkyl group, aryl group, or alkoxy group; and R2, R3, and R4 independently denote a hydrogen atom, furyl group, pyridyl group, alkyl group, or aryl group, are produced by cyclizing by heating an acylhydrazone derivative represented by the formula Image where R1, R2, R3, and R4 are defined as above, to produce compounds having useful anti-cerebral edema activity.

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