Process for producing 2,2'-cyclocytidine and analogues thereof

Details Process for producing 2,2'-cyclocytidine and analogues thereof Process for producing 2,2'-cyclocytidine and analogues thereof

C - Chemistry, Metallurgy

07

H

260/229.4

C07H 19/24 (2006.01) C07H 19/06 (2006.01) C07H 23/00 (2006.01)

Patent

CA 2012093

A novel process for the production of 2,2'- cyclocytidine compounds and pharmaceutically acceptable salts thereof comprises reacting a 2',3'-O- dialkylstannylene cytidine compound with an amine in the presence of a sulfonyl compound. 2,2'-Cyclocytidine is a percursor to cytarabine, a known antineoplastic and antiviral agent.

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