Process for producing 2-fluorine-1-cyclopropane carboxylic...

Details Process for producing 2-fluorine-1-cyclopropane carboxylic... Process for producing 2-fluorine-1-cyclopropane carboxylic...

C - Chemistry, Metallurgy

07

C

C07C 69/74 (2006.01) C07C 67/317 (2006.01) C07C 231/12 (2006.01) C07C 233/58 (2006.01)

Patent

CA 2255761

Cyclopropane carboxylic acid derivatives are advantageously produced by reacting halogen cyclopropane carboxylic acid derivatives with metals in the presence of bases and with or without the addition of hydrogen if the bases are added during the reaction. The process of the invention provides good yields and selectivities and a high proportion of cis-isomers in the reaction product.

On fabrique avantageusement des dérivés de l'acide 2-fluoro-1-cyclopropane carboxylique en faisant réagir des dérivés de l'acide halogénocyclopropane carboxylique avec des métaux en présence de bases, avec ou sans adjonction d'hydrogène, si l'on ajoute les bases durant la réaction. Le procédé a un bon rendement et une bonne sélectivité, et donne un pourcentage élevé d'isomères cis dans le produit de réaction.

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