Process for producing 2-isocyanato-2,3-dehydro carboxylic...

Details Process for producing 2-isocyanato-2,3-dehydro carboxylic... Process for producing 2-isocyanato-2,3-dehydro carboxylic...

B - Operations, Transporting

01

J

260/455.6

B01J 23/36 (2006.01)

Patent

CA 1269396

ABSTRACT OF THE DISCLOSURE 2-isocyanato-2,3-dehydrocarboxylic acid esters having the general formula Image wherein R1 represents a straight-chain or branched (C1-C4)alkyl radical, a phenyl radical or a benzyl radical, and R2 represents hydrogen or a methyl radical and R3 represents a straight-chain or branched (C1-C16)alkyl radical, a (C3-C8)cycloalkyl radical, a (C1-C6)alkyl-mercapto radical or a phenyl radical, are pro- duced by reacting 2-azido-carboxylic acid esters having the general formula Image (II) in an inert solvent at a temperature of between 0 and 150°C in the presence of a perrhenate with phosgene or diphosgene. The compounds having the general formula (I) can be converted with benzyl alcohol or with tert-butyl alcohol into the correspond- ing 2- and BOC-protected 2,3-dehydro-2-aminocarboxylic acid esters, which are in turn valuable components for the synthesis of dehydro peptides.

503679

Affiliated with

Also associated with

Rating

Process for producing 2-isocyanato-2,3-dehydro carboxylic... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for producing 2-isocyanato-2,3-dehydro carboxylic..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for producing 2-isocyanato-2,3-dehydro carboxylic... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1167582