Process for producing 2-oxo-1-phenyl-3-oxabicyclo[3.1.0]hexane

Details Process for producing 2-oxo-1-phenyl-3-oxabicyclo[3.1.0]hexane Process for producing 2-oxo-1-phenyl-3-oxabicyclo[3.1.0]hexane

C - Chemistry, Metallurgy

07

D

C07D 307/93 (2006.01)

Patent

CA 2568901

The present invention provides a process for producing 2-oxo-1-phenyl-3-oxabicyclo[3.1.0]hexane which comprises reacting phenylacetonitrile with epichlorohydrin in the presence of sodium hydride. According to the present invention, 2-oxo-1-phenyl-3-oxabicyclo[3.1.0]hexane can be produced safely, easily and industrially advantageously.

La présente invention décrit un procédé de production du 2-oxo-1-phényl-3-oxabicyclo[3.1.0]hexane qui comprend une étape pour faire réagir la phényl acétonitrile avec l~épichlorohydrine en présence d~hydrure de sodium. Avec ce procédé, le 2-oxo-1-phényl-3-oxabicyclo[3.1.0]hexane peut être produit sans danger, simplement et avantageusement sur le plan commercial.

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