Process for producing 3-amino-rifamycins s and sv

Details Process for producing 3-amino-rifamycins s and sv Process for producing 3-amino-rifamycins s and sv

C - Chemistry, Metallurgy

07

D

260/235.82

C07D 498/08 (2006.01)

Patent

CA 1095036

ABSTRACT OF THE DISCLOSURE : Method of preparing 3-amino-rifamycins S and SV having antibiotic activity. According to such a method a 3-bromo- rifamycin S is reacted with sodium nitrite to give 3-nitro- rifamycin S which is reduced with zinc powder to give the 3- amino-rifamycin SV from which the 3-amino-rifamycin S can be obtained by treatment with an oxidating agent.

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