Process for producing 3-aminomethyltetrahydrofuran derivative

C - Chemistry – Metallurgy – 07 – D

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C07D 307/14 (2006.01)

Patent

CA 2568800

Disclosed is a method for highly efficiently producing a 3- aminomethyltetrahydrofuran derivative from a low-cost industrial raw material. Specifically, a 3-cyanotetrahydrofuran derivative is produced at high yield from a low-cost, industrially easily-available malic acid derivative, and then a 3-aminomethyltetrahydrofuran derivative is produced by reducing the cyano group of the 3-cyanotetrahydrofuran derivative.

L~invention décrit un procédé pour produire avec un rendement élevé un dérivé de 3-aminométhyltétrahydrofurane à partir d~une matière première industrielle bon marché. En particulier, un dérivé de 3-cyanotétrahydrofurane est produit avec un rendement élevé à partir d~un dérivé d~acide malique bon marché facilement disponible dans le commerce, et ensuite un dérivé de 3-aminométhyltétrahydrofurane est produit en réduisant le groupe cyano du dérivé de 3-cyanotétrahydrofurane.

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