Process for producing 3-phenoxybenzyl 2-(4-...

C - Chemistry – Metallurgy – 07 – C

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C07C 43/29 (2006.01) C07C 41/16 (2006.01) C07C 41/24 (2006.01) C07C 41/30 (2006.01) C07C 43/225 (2006.01) C07C 43/267 (2006.01)

Patent

CA 1241026

ABSTRACT The present invention relates to a process for producing 3-phenoxybenzyl 2-(4-alkoxyphenyl)- 2-methylpropyl ethers having excellent insecticidal and acaricidal activities which are represented by formula (IV): Image (IV) wherein R is a lower alkyl group and X1 and X2 are each a hydrogen or fluorine atom, which comprises reacting a 3-halogeno-4-alkoxy- neophyl halide represented by the formula (I): Image (I) wherein Y1 and Y2 are each a hydorgen, chlo- rine or bromine atom, at least one of them being a chlorine or bromine atom, R has the same meaning as above and X is a halogen atom, with a 3-phenoxybenzyl alcohol represented by the formula (II): Image (II) wherein X1 and X2 have the same meaning as - above, in the presence of a base to obtain a 3-phenoxy- benzyl 2-(4-alkoxy-3-halogenophenyl)-2-methyl- propyl ether represented by the formula (III): Image (III) wherein Y1, Y2, R, X1 and X2 have the same meaning as above, and then subjecting the product to a hydrodehalogenation reaction, and relates to a process for producing a 3- halogeno-4-alkoxyneophyl halide represented by formula (I), which comprises reacting a 2-halogeno-1-alkoxybenzene represented by formula (V): Image (V) wherein Y1 and Y2 are each a hydrogen, chlo- rine or bromine atom, at least one of them being a chlorine or bromine atom, and R re- presents a lower alkyl group, with a methallyl halide in the presence of an acid catalyst at -20 to 50°C.

438584

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