Process for producing 4-ring-substituted phenyl lower alkyl...

C - Chemistry – Metallurgy – 07 – C

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C07C 49/76 (2006.01) C07C 45/46 (2006.01)

Patent

CA 1268778

ABSTRACT OF THE INVENTION The production of a 4-lower alkyl or 4-phenyl ring-substituted phenyl lower alkyl ketone, e.g. 4-methylacetophenone, 4-ethylacetophenone or 4-phenylacetophenone, is carried out by reacting a lower alkyl- or phenyl-substituted benzene, e.g. toluene, ethylbenzene, or biphenyl, with a lower alkanoic acid, e.g. acetic acid, at an elevated temperature in the presence of a medium pore, pentasil-type molecular sieve, e.g. an H-ZSM-5 zeolite, a silicalite or an AMS-1B borosilicate, as catalyst.

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