Process for producing a sterile prednisolone gel

Details Process for producing a sterile prednisolone gel Process for producing a sterile prednisolone gel

A - Human Necessities

61

K

A61K 31/57 (2006.01) A61K 9/06 (2006.01) A61K 47/32 (2006.01)

Patent

CA 2183331

The invention concerns a method for producing a sterile prednisolone gel. The method is characterized in that prednisolone or its pharmaceutically acceptable ester is sterilized and incorporated into a sterile polyacrylate gel, which has been per se conventionally produced, in appropriate amount under aseptic conditions, or else the sterile prednisolone or its pharmaceutically acceptable ester is suspended in a part of the amount of water required for producing the polyacrylate suspension and is then homogenously incorporated into the polyacryate, which is then made into a gel.

Selon un procédé de production d'un gel stérile de prednisolone, on produit de manière connue en soi un gel stérile de polyacrylate, on stérilise la prednisolone ou ses esters pharmaceutiquement admissibles et on l'incorpore en quantités appropriées dans des conditions aseptiques au gel de polyacrylate, ou on met la prednisolone stérile ou ses esters en suspension dans une partie de la quantité d'eau requise pour produire la suspension de polyacrylate, on les incorpore de manière homogène au polyacrylate et on transforme ensuite celui-ci en un gel.

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