Process for producing amidine sulfonic acid intermediates...

C - Chemistry – Metallurgy – 07 – C

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C07C 309/02 (2006.01) C07C 381/14 (2006.01) C07D 207/273 (2006.01) C07D 233/42 (2006.01) C07D 239/10 (2006.01) C07D 295/215 (2006.01)

Patent

CA 1300629

PROCESS FOR PRODUCING AMIDINE SULFONIC ACID INTERMEDIATES FOR GUANIDINES Abstract An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): (III) Image Image (II) with H2O2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps. MN 442

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