Process for producing antithrombin iii composition

C - Chemistry – Metallurgy – 07 – K

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Details

C07K 14/47 (2006.01) A61K 38/57 (2006.01) A61P 7/02 (2006.01) C07K 14/81 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2542035

It is intended to provide a process for producing an antithrombin III composition comprising a genetically modified antithrombin III molecule having an N-glycoside-binding complex sugar chain, which has an N-glycoside-binding complex sugar chain having no fucose attached to N-acetylglucosamine at the reducing end of the sugar chain.

Cette invention concerne un procédé permettant de produire une composition d'antithrombine III comprenant une molécule d'antithrombine III génétiquement modifiée présentant une chaîne glucidique complexe à liaison au N-glycoside, laquelle chaîne glucidique ne présente aucun fucose relié à N-acétylglucosamine à son extrémité de réduction.

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